A hydrogel-based enzyme-loaded polymersome reactor

• Main Authors: De Hoog, Hans-Peter M., Arends, Isabel W. C. E., Rowan, Alan E., Cornelissen, Jeroen J. L. M., Nolte, Roeland J. M.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2011
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/94036; http://hdl.handle.net/10220/6970
• Institution: Nanyang Technological University

In this study we report the immobilization of enzyme-containing polymersomes into a macromolecular hydrogel. Whereas free enzyme shows progressive leakage from the hydrogel in a period of days, leakage of the polymersome-protected enzyme is virtually absent. The preparation of the hydrogel occurs un...