High-throughput polymerase chain reaction in parallel circular loops using magnetic actuation

• Main Authors: Sun, Yi, Nguyen, Nam-Trung, Kwok, Yien Chian
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Engineering::Mechanical engineering
• Online Access: https://hdl.handle.net/10356/94178; http://hdl.handle.net/10220/7841
• Institution: Nanyang Technological University

We report here a novel multichannel closed-loop magnetically actuated microchip for high-throughput polymerase chain reaction (PCR). This is achieved by designing a series of concentric circular channels on one microchip and exploiting a magnetic force to drive DNA samples flowing continuously throu...