Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor

Shc is a widely expressed adapter protein that plays an important role in signaling via a variety of cell surface receptors and has been implicated in coupling the stimulation of growth factor, cytokine, and antigen receptors to the Ras signaling pathway. She interacts with several tyrosine-phosphor...

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Bibliographic Details
Main Authors: Meadows, Robert P., Logan, Timothy M., Wade, Warren S., Ravichandran, Kodimangalam S., Burakoffe, Steven J., Fesik, Stephen W., Zhou, Ming-Ming, Yoon, Ho Sup
Other Authors: School of Biological Sciences
Format: Conference or Workshop Item
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/94261
http://hdl.handle.net/10220/7506
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Institution: Nanyang Technological University
Language: English
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