Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor
Shc is a widely expressed adapter protein that plays an important role in signaling via a variety of cell surface receptors and has been implicated in coupling the stimulation of growth factor, cytokine, and antigen receptors to the Ras signaling pathway. She interacts with several tyrosine-phosphor...
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Main Authors: | Meadows, Robert P., Logan, Timothy M., Wade, Warren S., Ravichandran, Kodimangalam S., Burakoffe, Steven J., Fesik, Stephen W., Zhou, Ming-Ming, Yoon, Ho Sup |
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Other Authors: | School of Biological Sciences |
Format: | Conference or Workshop Item |
Language: | English |
Published: |
2012
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/94261 http://hdl.handle.net/10220/7506 |
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Institution: | Nanyang Technological University |
Language: | English |
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