Nanotopographic carbon nanotube thin-film substrate freezes lateral motion of secretory vesicles
Thin-film carbon-nanotube networks can interface with living neuroendocrine PC12 cells and support their growth and proliferation. Interestingly, as revealed by total-internal-reflection fluorescence microscopy, the nanoroughness created by the carbon-nanotube net physically deforms the 5 nm thick c...
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| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/94280 http://hdl.handle.net/10220/7488 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Thin-film carbon-nanotube networks can interface with living neuroendocrine PC12 cells and support their growth and proliferation. Interestingly, as revealed by total-internal-reflection fluorescence microscopy, the nanoroughness created by the carbon-nanotube net physically deforms the 5 nm thick cell membrane with high local curvature, and significantly impedes the lateral motion of subplasmalemmal secretory vesicles. |
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