Genome-wide inferring gene-phenotype relationship by walking on the heterogeneous network

• Main Authors: Li, Yongjin, Patra, Jagdish Chandra
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2011
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• Online Access: https://hdl.handle.net/10356/94345; http://hdl.handle.net/10220/7252
• Institution: Nanyang Technological University

Motivation: Clinical diseases are characterized by distinct phenotypes. To identify disease genes is to elucidate the gene–phenotype relationships. Mutations in functionally related genes may result in similar phenotypes. It is reasonable to predict disease-causing genes by integrating phenotypic da...