Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots

Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots

It has been increasingly recognized that adenosine-5 ′ -triphosphate (ATP) signaling through P2 purinergic receptors has a diverse infl uence on cell functions and human health. In this contribution, a simple and non-invasive method to specifi cally label P2 receptors using ATP-...

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Main Authors: Jiang, Shan, Liu, Aiping, Duan, Hongwei, Soo, Jianchow, Chen, Peng
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2012
Subjects:
DRNTU::Engineering::Chemical engineering
Online Access:https://hdl.handle.net/10356/94388
http://hdl.handle.net/10220/7492
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-943882020-03-07T11:35:34Z Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots Jiang, Shan Liu, Aiping Duan, Hongwei Soo, Jianchow Chen, Peng School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering It has been increasingly recognized that adenosine-5 ′ -triphosphate (ATP) signaling through P2 purinergic receptors has a diverse infl uence on cell functions and human health. In this contribution, a simple and non-invasive method to specifi cally label P2 receptors using ATP-conjugated quantum dots (QDs) is demonstrated. In addition, the endocytosis, vesicular traffi cking, and recycling of QD-labeled P2 receptors are studied under different physiological conditions using confocal and total internal refl ection fl uorescence microscopy. 2012-02-02T05:26:46Z 2019-12-06T18:55:20Z 2012-02-02T05:26:46Z 2019-12-06T18:55:20Z 2011 2011 Journal Article Jiang, S., Liu, A., Duan, H., Soo, J., & Chen, P. (2011). Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots. Advanced Functional Materials, 21, 2776–2780. 1616-301X https://hdl.handle.net/10356/94388 http://hdl.handle.net/10220/7492 10.1002/adfm.201100472 163176 en Advanced functional materials © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim 5 p.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Engineering::Chemical engineering
spellingShingle DRNTU::Engineering::Chemical engineering
Jiang, Shan
Liu, Aiping
Duan, Hongwei
Soo, Jianchow
Chen, Peng
Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots
description It has been increasingly recognized that adenosine-5 ′ -triphosphate (ATP) signaling through P2 purinergic receptors has a diverse infl uence on cell functions and human health. In this contribution, a simple and non-invasive method to specifi cally label P2 receptors using ATP-conjugated quantum dots (QDs) is demonstrated. In addition, the endocytosis, vesicular traffi cking, and recycling of QD-labeled P2 receptors are studied under different physiological conditions using confocal and total internal refl ection fl uorescence microscopy.
author2 School of Chemical and Biomedical Engineering
author_facet School of Chemical and Biomedical Engineering
Jiang, Shan
Liu, Aiping
Duan, Hongwei
Soo, Jianchow
Chen, Peng
format Article
author Jiang, Shan
Liu, Aiping
Duan, Hongwei
Soo, Jianchow
Chen, Peng
author_sort Jiang, Shan
title Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots
title_short Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots
title_full Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots
title_fullStr Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots
title_full_unstemmed Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots
title_sort labeling and tracking p2 purinergic receptors in living cells using atp-conjugated quantum dots
publishDate 2012
url https://hdl.handle.net/10356/94388
http://hdl.handle.net/10220/7492
_version_ 1681040246720954368

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