Biomimetic processing of bioactive interface on silicon substrates

To facilitate the implantation of silicon-based devices in vivo, the presence of a biocompatible and bioactive coating is noted to be an essential factor. The objective of this present work is therefore to explore a relatively simple and low cost process to induce the formation of bioactive apatite...

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Bibliographic Details
Main Authors: Chong, S. C., Loo, Say Chye Joachim, Lee, Pooi See, Ma, Jan
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/94398
http://hdl.handle.net/10220/8514
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Institution: Nanyang Technological University
Language: English
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Summary:To facilitate the implantation of silicon-based devices in vivo, the presence of a biocompatible and bioactive coating is noted to be an essential factor. The objective of this present work is therefore to explore a relatively simple and low cost process to induce the formation of bioactive apatite on silicon. The formation of apatite on silicon was carried out by a biomimetic approach on two orientations of silicon wafer, namely (100) and (111). The samples are functionalized by chemical etching, followed by incubation in a simulated body fluid. Scanning electron microscopy, energy dispersive X-ray analysis, X-ray diffraction analysis, and X-ray photoelectron spectroscopy were carried out. It was found that the growth of apatite is dependent on the orientation of the silicon wafer. Cell culturing experiment further verified the biological performance of the apatite-coated silicon samples.