Design of β-hairpin peptides for modulation of cell adhesion by β-turn constraint

• Main Authors: Satyanarayanajois, Seetharama D., Giddu, Sumana, Subramanian, Vivekanandan, Yoon, Ho Sup
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: https://hdl.handle.net/10356/94527; http://hdl.handle.net/10220/7477
• Institution: Nanyang Technological University

The CD2−CD58 interaction in immune regulation and disease pathology has provided new targets for developing potential immunosuppressive agents. In the present study, we report the introduction of constraints to generate β-hairpin structures from the strand sequences of CD2 protein. The β-hairpin str...