Brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols
A proton does the two jobs: Brønsted acids alone catalyze the α-alkylation of aldehydes with diaryl alcohols. In this type of transformation, the acid-catalysis approach offers a broader substrate scope compared to the previously used enamine catalysis methods. The acid plays two important roles: on...
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2012
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sg-ntu-dr.10356-946312020-03-07T12:31:29Z Brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols Xing, Chong Sun, Hui Zhang, Junmin Li, Guohui Chi, Robin Yonggui School of Physical and Mathematical Sciences A proton does the two jobs: Brønsted acids alone catalyze the α-alkylation of aldehydes with diaryl alcohols. In this type of transformation, the acid-catalysis approach offers a broader substrate scope compared to the previously used enamine catalysis methods. The acid plays two important roles: one is to mediate the alcohol dehydration for carbocation formation; the other is to accelerate the rate-determining aldehyde enolization. 2012-05-22T09:10:43Z 2019-12-06T18:59:29Z 2012-05-22T09:10:43Z 2019-12-06T18:59:29Z 2011 2011 Journal Article Xing, C., Sun, H., Zhang, J., Li, G. & Chi, R. Y. (2011). Brønsted Acid Catalyzed α-Alkylation of Aldehydes with Diaryl Methyl Alcohols. Chemistry - A European Journal, 17(44), 12272-12275. https://hdl.handle.net/10356/94631 http://hdl.handle.net/10220/8118 10.1002/chem.201102623 165054 en Chemistry - a European journal © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
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A proton does the two jobs: Brønsted acids alone catalyze the α-alkylation of aldehydes with diaryl alcohols. In this type of transformation, the acid-catalysis approach offers a broader substrate scope compared to the previously used enamine catalysis methods. The acid plays two important roles: one is to mediate the alcohol dehydration for carbocation formation; the other is to accelerate the rate-determining aldehyde enolization. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Xing, Chong Sun, Hui Zhang, Junmin Li, Guohui Chi, Robin Yonggui |
| format |
Article |
| author |
Xing, Chong Sun, Hui Zhang, Junmin Li, Guohui Chi, Robin Yonggui |
| spellingShingle |
Xing, Chong Sun, Hui Zhang, Junmin Li, Guohui Chi, Robin Yonggui Brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols |
| author_sort |
Xing, Chong |
| title |
Brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols |
| title_short |
Brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols |
| title_full |
Brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols |
| title_fullStr |
Brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols |
| title_full_unstemmed |
Brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols |
| title_sort |
brønsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols |
| publishDate |
2012 |
| url |
https://hdl.handle.net/10356/94631 http://hdl.handle.net/10220/8118 |
| _version_ |
1681034951027326976 |