HIV reservoirs and immune surveillance evasion cause the failure of structured treatment interruptions : a computational study

• Main Authors: Mancini, Emiliano, Castiglione, Filippo, Bernaschi, Massimo, De Luca, Andrea, Sloot, Peter M. A.
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/94952; http://hdl.handle.net/10220/9358
• Institution: Nanyang Technological University

Continuous antiretroviral therapy is currently the most effective way to treat HIV infection. Unstructured interruptions are quite common due to side effects and toxicity, among others, and cannot be prevented. Several attempts to structure these interruptions failed due to an increased morbidity co...