Mitotic histone H3 phosphorylation by vaccinia-related kinase 1 in mammalian cells

• Main Authors: Kang, Tae-Hong, Park, Do-Young, Choi, Yoon Ha, Kim, Kyung-Jin, Yoon, Ho Sup, Kim, Kyong-Tai
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: https://hdl.handle.net/10356/95026; http://hdl.handle.net/10220/8519
• Institution: Nanyang Technological University

Mitotic chromatin condensation is essential for cell division in eukaryotes. Posttranslational modification of the N-terminal tail of histone proteins, particularly by phosphorylation by mitotic histone kinases, may facilitate this process. In mammals, aurora B is believed to be the mitotic histone...