Molecular characterization of the recombinant A-chain of a Type II ribosome-inactivating protein (RIP) from viscum album coloratum and structural basis on its ribosome-inactivating activity and the sugar-binding properties of the B-chain

• Main Authors: Kang, Cong Bao, Ye, Wen-Hui, Nanga, Ravi Prakash Reddy, Song, Joo-Hye, Song, Seong Kyu, Yoon, Ho Sup
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Microbiology
• Online Access: https://hdl.handle.net/10356/95124; http://hdl.handle.net/10220/8824; http://www.jbmb.or.kr/fulltext/jbmb/view.php?vol=39&page=560
• Institution: Nanyang Technological University

Mistletoe (Viscum album) lectins, which are classified as a type II ribosome-inactivating protein (RIP) due to their unique biological function and the potential medical and therapeutic application in cancer cells, receive a rising attention. The heterodimeric glycoproteins contain the Achain with c...