FKBP family proteins : immunophilins with versatile biological functions

• Main Authors: Kang, Cong Bao, Ye, Hong, Dhe-Paganon, Sirano, Yoon, Ho Sup
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/95238; http://hdl.handle.net/10220/8409
• Institution: Nanyang Technological University

Immunophilins consist of a family of highly conserved proteins binding with immunosuppressive drugs such as FK506, rapamycin and cyclosporin A. FK506-binding protein (FKBP) is one of two major immunophilins and most of FKBP family members bind FK506 and show peptidylproly...