Structure and binding interface of the cytosolic tails of αXβ2 integrin

• Main Authors: Chua, Geok-Lin, Tang, Xiao-Yan, Patra, Alok Tanala, Tan, Suet Mien, Bhattacharjya, Surajit
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/95359; http://hdl.handle.net/10220/9197
• Institution: Nanyang Technological University

Integrins are signal transducer proteins involved in a number of vital physiological processes including cell adhesion, proliferation and migration. Integrin molecules are hetero-dimers composed of two distinct subunits, α and β. In humans, 18 α and 8 β subunits are combined into 24 different integr...