Development of piezoelectric ultrasonic thrombolysis device for blood clot emulsification

Ultrasonic thrombolysis is an effective method to treat blood clot thrombus in a blood vessel. This paper reports an OD 5 mm and an OD 10 mm piezoelectric thrombolysis transducers that vibrate longitudinally and generate a pressure field at the distal vibration tip. Studies of vibration mode, pressu...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Low, Adrian F., Li, Tao, Ma, Jan, Kumar, Dinesh
مؤلفون آخرون: School of Materials Science & Engineering
التنسيق: مقال
اللغة:English
منشور في: 2012
الموضوعات:
الوصول للمادة أونلاين:https://hdl.handle.net/10356/95524
http://hdl.handle.net/10220/8312
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
المؤسسة: Nanyang Technological University
اللغة: English
الوصف
الملخص:Ultrasonic thrombolysis is an effective method to treat blood clot thrombus in a blood vessel. This paper reports an OD 5 mm and an OD 10 mm piezoelectric thrombolysis transducers that vibrate longitudinally and generate a pressure field at the distal vibration tip. Studies of vibration mode, pressure field pattern, and cavitation effect were carried out. The transducers were also tested for blood clot emulsification. The results indicate both transducers are effective. The OD 10 mm transducer with a long transmission wire has shown to provide a strong cavitation effect and work effectively at low frequency, high amplitude, and high power conditions. The OD 5 mm transducer was found to operate effectively under higher frequency, low amplitude, and lower power conditions. The cavitation effect is moderate, which facilitates precision and controls over obtaining a more uniform emulsification result.