Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers

An efficient rhodium-catalyzed synthesis of 2H-azirines and pyrroles has been developed. Novel rearrangement of α-oximino ketenes derived from α-diazo oxime ethers provides 2H-azirines bearing quaternary centers and allows for subsequent rearrangement to highly substituted pyrroles in excellent yiel...

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Main Authors: Jiang, Yaojia, Chan, Wei Chuen, Park, Cheol-Min
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/95800
http://hdl.handle.net/10220/11202
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-958002020-03-07T12:37:21Z Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers Jiang, Yaojia Chan, Wei Chuen Park, Cheol-Min School of Physical and Mathematical Sciences An efficient rhodium-catalyzed synthesis of 2H-azirines and pyrroles has been developed. Novel rearrangement of α-oximino ketenes derived from α-diazo oxime ethers provides 2H-azirines bearing quaternary centers and allows for subsequent rearrangement to highly substituted pyrroles in excellent yields. 2013-07-11T06:06:58Z 2019-12-06T19:21:48Z 2013-07-11T06:06:58Z 2019-12-06T19:21:48Z 2012 2012 Journal Article Jiang, Y., Chan, W. C., & Park, C. M. (2012). Expedient Synthesis of Highly Substituted Pyrroles via Tandem Rearrangement of α-Diazo Oxime Ethers. Journal of the American Chemical Society, 134(9), 4104-4107. https://hdl.handle.net/10356/95800 http://hdl.handle.net/10220/11202 10.1021/ja300552c en Journal of the American chemical society © 2012 American Chemical Society.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
description An efficient rhodium-catalyzed synthesis of 2H-azirines and pyrroles has been developed. Novel rearrangement of α-oximino ketenes derived from α-diazo oxime ethers provides 2H-azirines bearing quaternary centers and allows for subsequent rearrangement to highly substituted pyrroles in excellent yields.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Jiang, Yaojia
Chan, Wei Chuen
Park, Cheol-Min
format Article
author Jiang, Yaojia
Chan, Wei Chuen
Park, Cheol-Min
spellingShingle Jiang, Yaojia
Chan, Wei Chuen
Park, Cheol-Min
Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers
author_sort Jiang, Yaojia
title Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers
title_short Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers
title_full Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers
title_fullStr Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers
title_full_unstemmed Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers
title_sort expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers
publishDate 2013
url https://hdl.handle.net/10356/95800
http://hdl.handle.net/10220/11202
_version_ 1681046948215259136