Preparation of nanoparticles of poorly water-soluble antioxidant curcumin by antisolvent precipitation methods

• Main Authors: Kakran, Mitali, Sahoo, Nanda Gopal, Tan, I-Lin, Li, Lin
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/95946; http://hdl.handle.net/10220/11427
• Institution: Nanyang Technological University

The objective of this study was to enhance the solubility and dissolution rate of a poorly water-soluble antioxidant, curcumin, by fabricating its nanoparticles with two methods: antisolvent precipitation with a syringe pump (APSP) and evaporative precipitation of nanosuspension (EPN). For APSP, pro...