Ternary dispersions to enhance solubility of poorly water soluble antioxidants

• Main Authors: Kakran, Mitali, Sahoo, Nanda Gopal, Tan, Yong Wah, Li, Lin
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Mechanical engineering::Fluid mechanics
• Online Access: https://hdl.handle.net/10356/99780; http://hdl.handle.net/10220/17612
• Institution: Nanyang Technological University

The main aim of this study was to enhance the solubility and dissolution rate of the two poorly water-soluble antioxidants, curcumin (CUR) and hesperetin (HSP). Binary dispersions of the two drugs in the polymer, polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG) matrix were prepared. A surfact...