Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines
A highly reactive, chemo- and enantioselective addition of diphenylphosphine to α,β-unsaturated imines catalyzed by a palladacycle has been developed, thus providing the access to a series of chiral tertiary enaminophosphines in high yields. A putative catalytic cycle has also been proposed.
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2013
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sg-ntu-dr.10356-961452020-03-07T12:37:07Z Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines Pullarkat, Sumod A. Huang, Yinhua Chew, Renta Jonathan Li, Yongxin Leung, Pak-Hing School of Physical and Mathematical Sciences A highly reactive, chemo- and enantioselective addition of diphenylphosphine to α,β-unsaturated imines catalyzed by a palladacycle has been developed, thus providing the access to a series of chiral tertiary enaminophosphines in high yields. A putative catalytic cycle has also been proposed. 2013-10-30T04:34:52Z 2019-12-06T19:26:19Z 2013-10-30T04:34:52Z 2019-12-06T19:26:19Z 2012 2012 Journal Article Huang, Y., Chew, R. J., Pullarkat, S. A., Li, Y., & Leung, P.-H. (2012). Asymmetric Synthesis of Enaminophosphines via Palladacycle-Catalyzed Addition of Ph 2 PH to α,β-Unsaturated Imines . The Journal of Organic Chemistry, 77(16), 6849-6854. https://hdl.handle.net/10356/96145 http://hdl.handle.net/10220/17050 10.1021/jo300893s en The journal of organic chemistry |
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| description |
A highly reactive, chemo- and enantioselective addition of diphenylphosphine to α,β-unsaturated imines catalyzed by a palladacycle has been developed, thus providing the access to a series of chiral tertiary enaminophosphines in high yields. A putative catalytic cycle has also been proposed. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Pullarkat, Sumod A. Huang, Yinhua Chew, Renta Jonathan Li, Yongxin Leung, Pak-Hing |
| format |
Article |
| author |
Pullarkat, Sumod A. Huang, Yinhua Chew, Renta Jonathan Li, Yongxin Leung, Pak-Hing |
| spellingShingle |
Pullarkat, Sumod A. Huang, Yinhua Chew, Renta Jonathan Li, Yongxin Leung, Pak-Hing Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines |
| author_sort |
Pullarkat, Sumod A. |
| title |
Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines |
| title_short |
Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines |
| title_full |
Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines |
| title_fullStr |
Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines |
| title_full_unstemmed |
Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines |
| title_sort |
asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of ph2ph to α,β-unsaturated imines |
| publishDate |
2013 |
| url |
https://hdl.handle.net/10356/96145 http://hdl.handle.net/10220/17050 |
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1681045949957275648 |