In-vivo evaluation of an in situ polymer precipitation delivery system for a novel natriuretic peptide

• Main Authors: Venkatraman, Subbu S., Burnett Jr, John C., Chen, Horng H., Lim, Soo Ghim
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/96294; http://hdl.handle.net/10220/11906
• Institution: Nanyang Technological University

This study reports on the release of a novel natriuretic peptide, CD-NP, from an in situ polymer precipitation delivery system. Following extensive screening of in-vitro release profiles, an in-vivo evaluation of the efficacy of the delivery system was carried out in Wistar rats. Gel injection was p...