Dorsal activity of maternal squint is mediated by a non-coding function of the RNA

• Main Authors: Lim, S., Kumari, P., Gilligan, P., Quach, H. N. B., Mathavan, S., Sampath, Karuna.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/96891; http://hdl.handle.net/10220/13181
• Institution: Nanyang Technological University

Despite extensive study, the earliest steps of vertebrate axis formation are only beginning to be elucidated. We previously showed that asymmetric localization of maternal transcripts of the conserved zebrafish TGFβ factor Squint (Sqt) in 4-cell stage embryos predicts dorsal, preceding nuclear accum...