High productivity chromatography refolding process for Hepatitis B Virus X (HBx) protein guided by statistical design of experiment studies
The Hepatitis B Virus X (HBx) protein is a potential therapeutic target for the treatment of hepatocellular carcinoma. However, consistent expression of the protein as insoluble inclusion bodies in bacteria host systems has largely hindered HBx manufacturing via economical biosynthesis routes, there...
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| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/96977 http://hdl.handle.net/10220/11668 |
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| Institution: | Nanyang Technological University |
| Language: | English |