Self-assembled amorphous drug–polyelectrolyte nanoparticle complex with enhanced dissolution rate and saturation solubility

The dissolution rate and solubility of poorly soluble drugs can be enhanced by formulating them into stable amorphous nanoparticle complex (nanoplex). For this purpose, a highly sustainable self-assembly drug–polyelectrolyte complexation process is developed, with ciprofloxacin and dextran sulfate a...

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Main Authors: Cheow, Wean Sin, Hadinoto, Kunn
其他作者: School of Chemical and Biomedical Engineering
格式: Article
語言:English
出版: 2013
主題:
在線閱讀:https://hdl.handle.net/10356/97005
http://hdl.handle.net/10220/11623
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機構: Nanyang Technological University
語言: English