Self-assembled amorphous drug–polyelectrolyte nanoparticle complex with enhanced dissolution rate and saturation solubility
The dissolution rate and solubility of poorly soluble drugs can be enhanced by formulating them into stable amorphous nanoparticle complex (nanoplex). For this purpose, a highly sustainable self-assembly drug–polyelectrolyte complexation process is developed, with ciprofloxacin and dextran sulfate a...
Saved in:
Main Authors: | Cheow, Wean Sin, Hadinoto, Kunn |
---|---|
Other Authors: | School of Chemical and Biomedical Engineering |
Format: | Article |
Language: | English |
Published: |
2013
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/97005 http://hdl.handle.net/10220/11623 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Green preparation of antibiotic nanoparticle complex as potential anti-biofilm therapeutics via self-assembly amphiphile–polyelectrolyte complexation with dextran sulfate
by: Cheow, Wean Sin, et al.
Published: (2013) -
Carboxymethyl cellulose is a superior polyanion to dextran sulfate in stabilizing and enhancing the solubility of amorphous drug-polyelectrolyte nanoparticle complex
by: Dong, Bingxue, et al.
Published: (2020) -
Green amorphous nanoplex as a new supersaturating drug delivery system
by: Cheow, Wean Sin, et al.
Published: (2013) -
Assessing the permeability of supersaturating drug delivery system of amorphous drug-polyelectrolyte/protein nanoplexes in Caco-2 cell monolayer
by: Tran, The-Thien, et al.
Published: (2024) -
Amorphous ternary nanoparticle complex of curcumin-chitosan-hypromellose exhibiting built-in solubility enhancement and physical stability of curcumin
by: Wong, Jerome Jie Long, et al.
Published: (2019)