The mechanics behind DNA sequence-dependent properties of the nucleosome

• Main Authors: Chua, Eugene Yue Dao, Vasudevan, Dileep, Davey, Gabriela Elzbieta, Wu, Bin, Davey, Curtis Alexander
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: https://hdl.handle.net/10356/97179; http://hdl.handle.net/10220/9991
• Institution: Nanyang Technological University

Chromatin organization and composition impart sophisticated regulatory features critical to eukaryotic genomic function. Although DNA sequence-dependent histone octamer binding is important for nucleosome activity, many aspects of this phenomenon have remained elusive. We studied nucleosome structur...