Bioconjugated pluronic triblock-copolymer Micelle-encapsulated quantum dots for targeted imaging of cancer : in vitro and in vivo studies

• Main Authors: Prasad, Paras N., Liu, Liwei, Yong, Ken-Tye, Roy, Indrajit, Law, Wing-Cheung, Ye, Ling, Liu, Jianwei, Liu, Jing, Kumar, Rajiv, Zhang, Xihe
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Electrical and electronic engineering
• Online Access: https://hdl.handle.net/10356/97423; http://hdl.handle.net/10220/11854
• Institution: Nanyang Technological University

Early in this study, CdTe/ZnS core/shell quantum dots (QDs) were encapsulated in carboxylated Pluronic F127 triblock polymeric micelle, to preserve the optical and colloidal stability of QDs in biological fluids. Folic acid (FA) was then conjugated to the surface of QDs for the targeted delivery of...