Matricellular proteins : a sticky affair with cancers

• Main Authors: Chong, Han Chung, Tan, Chek Kun, Huang, Royston-Luke, Tan, Nguan Soon
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/97780; http://hdl.handle.net/10220/17102
• Institution: Nanyang Technological University

The multistep process of metastasis is a major hallmark of cancer progression involving the cointeraction and coevolution of the tumor and its microenvironment. In the tumor microenvironment, tumor cells and the surrounding stromal cells aberrantly secrete matricellular proteins, which are a family...