Cosolvent effects on the drug release and depot swelling in injectable in situ depot-forming systems

• Main Authors: Liu, Hui, Venkatraman, Subbu S.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Medicine::Pharmacy::Pharmaceutical technology
• Online Access: https://hdl.handle.net/10356/97951; http://hdl.handle.net/10220/17160
• Institution: Nanyang Technological University

Although injectable depot-forming solutions have been commercialized, the factors that influence the overall release kinetics from such systems are still not fully understood. In this work, we address the effect of cosolvent on the issue of excessive burst release of potent bioactives from injectabl...