Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes

Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes

A facile and general method leading to polyfunctionalized quinolines was developed. In the presence of a highly efficient combination encompassing (PPh)3AuCl and AgOTf, the reactions between 2-aminocarbonyls and an array of internal alkynes proceeded smoothly to afford quinoline derivatives in good...

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Main Authors: Cai, Shuting, Zeng, Jing, Bai, Yaguang, Liu, Xue-Wei
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/98290
http://hdl.handle.net/10220/17051
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-982902020-03-07T12:34:46Z Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes Cai, Shuting Zeng, Jing Bai, Yaguang Liu, Xue-Wei School of Physical and Mathematical Sciences A facile and general method leading to polyfunctionalized quinolines was developed. In the presence of a highly efficient combination encompassing (PPh)3AuCl and AgOTf, the reactions between 2-aminocarbonyls and an array of internal alkynes proceeded smoothly to afford quinoline derivatives in good to excellent yields (up to 93%). 2013-10-30T04:36:59Z 2019-12-06T19:53:15Z 2013-10-30T04:36:59Z 2019-12-06T19:53:15Z 2011 2011 Journal Article Cai, S., Zeng, J., Bai, Y., & Liu, X.- W. (2012). Access to Quinolines through Gold-Catalyzed Intermolecular Cycloaddition of 2-Aminoaryl Carbonyls and Internal Alkynes. The Journal of Organic Chemistry, 77(1), 801-807. https://hdl.handle.net/10356/98290 http://hdl.handle.net/10220/17051 10.1021/jo202281x en The journal of organic chemistry © 2011 American Chemical Society
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
description A facile and general method leading to polyfunctionalized quinolines was developed. In the presence of a highly efficient combination encompassing (PPh)3AuCl and AgOTf, the reactions between 2-aminocarbonyls and an array of internal alkynes proceeded smoothly to afford quinoline derivatives in good to excellent yields (up to 93%).
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Cai, Shuting
Zeng, Jing
Bai, Yaguang
Liu, Xue-Wei
format Article
author Cai, Shuting
Zeng, Jing
Bai, Yaguang
Liu, Xue-Wei
spellingShingle Cai, Shuting
Zeng, Jing
Bai, Yaguang
Liu, Xue-Wei
Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes
author_sort Cai, Shuting
title Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes
title_short Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes
title_full Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes
title_fullStr Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes
title_full_unstemmed Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes
title_sort access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes
publishDate 2013
url https://hdl.handle.net/10356/98290
http://hdl.handle.net/10220/17051
_version_ 1681046521905152000

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