Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes

• Main Authors: Cai, Shuting, Zeng, Jing, Bai, Yaguang, Liu, Xue-Wei
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/98290; http://hdl.handle.net/10220/17051
• Institution: Nanyang Technological University

A facile and general method leading to polyfunctionalized quinolines was developed. In the presence of a highly efficient combination encompassing (PPh)3AuCl and AgOTf, the reactions between 2-aminocarbonyls and an array of internal alkynes proceeded smoothly to afford quinoline derivatives in good...