Synthesis of 3-Oxaterpenoids and its application in the total synthesis of (±)-moluccanic acid methyl ester

• Main Authors: Li, Bin, Lai, Yin-Chang, Zhao, Yujun, Wong, Yiu-Hang, Shen, Zhi-Liang, Loh, Teck-Peng
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Chemistry
• Online Access: https://hdl.handle.net/10356/98455; http://hdl.handle.net/10220/12483
• Institution: Nanyang Technological University

Cascades: An InBr3-catalyzed intermolecular polyene cyclization initiated by a Prins reaction provides a concise approach to 3-oxaterpenoid derivatives. The reaction is compatible with various aldehydes, ketones, and polyolefin–alcohol substrates. In addition, the total synthesis of (±)-moluccanic a...