Advances in mammalian cell line development technologies for recombinant protein production

• Main Authors: Lai, Tingfeng, Yang, Yuansheng, Ng, Say Kong
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine::Pharmacy::Pharmaceutical technology
• Online Access: https://hdl.handle.net/10356/98484; http://hdl.handle.net/10220/18419
• Institution: Nanyang Technological University

From 2006 to 2011, an average of 15 novel recombinant protein therapeutics have been approved by US Food and Drug Administration (FDA) annually. In addition, the expiration of blockbuster biologics has also spurred the emergence of biosimilars. The increasing numbers of innovator biologic products a...