Identifying and engineering promoters for high level and sustainable therapeutic recombinant protein production in cultured mammalian cells

Promoters are essential on plasmid vectors to initiate transcription of the transgenes when generating therapeutic recombinant proteins expressing mammalian cell lines. High and sustained levels of gene expression are desired during therapeutic protein production while gene expression is useful for...

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Bibliographic Details
Main Authors: Ho, Steven C. L., Yang, Yuansheng
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/81399
http://hdl.handle.net/10220/40783
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Institution: Nanyang Technological University
Language: English