Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish

Hedgehog (Hh) signaling is mediated by the Gli transcription factors and, in the zebrafish, plays an important role in patterning both the neural tube and myotome. Using a null allele of the gli2a gene induced by targeted mutagenesis, we show that Gli2a is completely dispensable in the fish but acts...

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Bibliographic Details
Main Authors: Wang, Xingang, Zhao, Zhonghua, Muller, Julius, Iyu, Audrey, Khng, Alexis Jiaying, Guccione, Ernesto, Ruan, Yijun, Ingham, Philip William
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2015
Online Access:https://hdl.handle.net/10356/98553
http://hdl.handle.net/10220/38599
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Institution: Nanyang Technological University
Language: English