The effect of curcumin on the stability of Aβ dimers

• Main Authors: Zhao, Li Na, Chiu, See-Wing, Benoit, Jérôme, Chew, Lock Yue, Mu, Yuguang
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Chemistry::Analytical chemistry::Proteins
• Online Access: https://hdl.handle.net/10356/98827; http://hdl.handle.net/10220/17215
• Institution: Nanyang Technological University

Aβ oligomers are potential targets for the diagnosis and therapy of Alzheimer’s disease (AD). On the other hand, the molecule curcumin has been shown to possess significant therapeutic potential in many areas. In this paper, we use all-atom explicit solvent molecular dynamics simulations to study th...