Asymmetric syntheses of 8-oxabicyclo[3,2,1]octanes : a cationic cascade cyclization

High octane: A novel and practical syntheses of 8-oxabicyclo[3.2.1]octanes using a cationic cascade cyclization reaction has been developed (see scheme; TIPS=triisopropylsilyl). The diastereomer of the cyclization product isolated depends upon whether the acetal or aldehyde substrate is used.

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Bibliographic Details
Main Authors: Li, Bin, Zhao, Yu-Jun, Lai, Yin-Chang, Loh, Teck-Peng
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/99014
http://hdl.handle.net/10220/12443
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Institution: Nanyang Technological University
Language: English