Cyclic tensile loading regulates human mesenchymal stem cell differentiation into neuron-like phenotype

• Main Authors: Leong, Wen Shing, Wu, Shu Cheng, Pal, Mintu, Tay, Chor Yong, Yu, Haiyang, Li, Huaqiong, Tan, Lay Poh
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/99272; http://hdl.handle.net/10220/17303
• Institution: Nanyang Technological University

Mechanical loading has been utilized as an effective tool to direct mesenchymal stem cells (MSCs) commitment into cell lineages of mesodermal origin. However, the use of this tool to induce transdifferentiation of MSCs into the neural lineage has never been attempted. In this study, we examined the...