Silver triflate catalyzed tandem heterocyclization/alkynylation of 1-((2-tosylamino)aryl)but-2-yne-1,4-diols to 2-alkynyl indoles

Silver triflate catalyzed tandem heterocyclization/alkynylation of 1-((2-tosylamino)aryl)but-2-yne-1,4-diols to 2-alkynyl indoles

Don't cross me! 2-Alkynyl indoles were prepared efficiently by the AgOTf-catalyzed tandem heterocyclization/alkynylation of 1-(2-tosylamino)aryl)but-2-yne-1,4-diols under mild conditions (see scheme). The attractiveness of this approach lies in the fact that both the indole ring and alkyne side...

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Bibliographic Details
Main Authors: Mothe, Srinivasa Reddy, Kothandaraman, Prasath, Lauw, Sherman Jun Liang, Chin, Samuel Ming Wei, Chan, Philip Wai Hong
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/99426
http://hdl.handle.net/10220/12940
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/99426
http://hdl.handle.net/10220/12940

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