Silver triflate catalyzed tandem heterocyclization/alkynylation of 1-((2-tosylamino)aryl)but-2-yne-1,4-diols to 2-alkynyl indoles
Don't cross me! 2-Alkynyl indoles were prepared efficiently by the AgOTf-catalyzed tandem heterocyclization/alkynylation of 1-(2-tosylamino)aryl)but-2-yne-1,4-diols under mild conditions (see scheme). The attractiveness of this approach lies in the fact that both the indole ring and alkyne side...
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Main Authors: | Mothe, Srinivasa Reddy, Kothandaraman, Prasath, Lauw, Sherman Jun Liang, Chin, Samuel Ming Wei, Chan, Philip Wai Hong |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Online Access: | https://hdl.handle.net/10356/99426 http://hdl.handle.net/10220/12940 |
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Institution: | Nanyang Technological University |
Language: | English |
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