Finding transcription factor binding motifs for coregulated genes by combining sequence overrepresentation with cross-species conservation

• Main Authors: Jia, Hui., Li, Jinming.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/99457; http://hdl.handle.net/10220/17264
• Institution: Nanyang Technological University

Novel computational methods for finding transcription factor binding motifs have long been sought due to tedious work of experimentally identifying them. However, the current prevailing methods yield a large number of false positive predictions due to the short, variable nature of transcriptional fa...