[4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines
The first example of phosphine catalyzed aza-Rauhut–Currier reaction initiated [4+2] annulation of vinyl ketones with N-sulfonyl-1-aza-1,3-dienes has been disclosed. Under the ambient conditions, this protocol provides a practical access to valuable densely functionalized tetrahydropyridines in good...
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/99501 http://hdl.handle.net/10220/12915 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | The first example of phosphine catalyzed aza-Rauhut–Currier reaction initiated [4+2] annulation of vinyl ketones with N-sulfonyl-1-aza-1,3-dienes has been disclosed. Under the ambient conditions, this protocol provides a practical access to valuable densely functionalized tetrahydropyridines in good to excellent yields and high diastereoselectivities (see scheme). |
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