[4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines

The first example of phosphine catalyzed aza-Rauhut–Currier reaction initiated [4+2] annulation of vinyl ketones with N-sulfonyl-1-aza-1,3-dienes has been disclosed. Under the ambient conditions, this protocol provides a practical access to valuable densely functionalized tetrahydropyridines in good...

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Main Authors: Zhong, Guofu, Leong, Wendy Wen Yi, Tong, Qinjie, Shi, Zugui
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/99501
http://hdl.handle.net/10220/12915
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-995012020-03-07T12:34:46Z [4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines Zhong, Guofu Leong, Wendy Wen Yi Tong, Qinjie Shi, Zugui School of Physical and Mathematical Sciences The first example of phosphine catalyzed aza-Rauhut–Currier reaction initiated [4+2] annulation of vinyl ketones with N-sulfonyl-1-aza-1,3-dienes has been disclosed. Under the ambient conditions, this protocol provides a practical access to valuable densely functionalized tetrahydropyridines in good to excellent yields and high diastereoselectivities (see scheme). 2013-08-02T06:27:12Z 2019-12-06T20:08:07Z 2013-08-02T06:27:12Z 2019-12-06T20:08:07Z 2012 2012 Journal Article Shi, Z., Tong, Q., Leong, W. W. Y.,& Zhong, G. (2012). [4+2] Annulation of Vinyl Ketones Initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier Reaction: A Practical Access to Densely Functionalized Tetrahydropyridines. Chemistry - A European Journal, 18(32), 9802-9806. 0947-6539 https://hdl.handle.net/10356/99501 http://hdl.handle.net/10220/12915 10.1002/chem.201201318 en Chemistry - a European journal
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
description The first example of phosphine catalyzed aza-Rauhut–Currier reaction initiated [4+2] annulation of vinyl ketones with N-sulfonyl-1-aza-1,3-dienes has been disclosed. Under the ambient conditions, this protocol provides a practical access to valuable densely functionalized tetrahydropyridines in good to excellent yields and high diastereoselectivities (see scheme).
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Zhong, Guofu
Leong, Wendy Wen Yi
Tong, Qinjie
Shi, Zugui
format Article
author Zhong, Guofu
Leong, Wendy Wen Yi
Tong, Qinjie
Shi, Zugui
spellingShingle Zhong, Guofu
Leong, Wendy Wen Yi
Tong, Qinjie
Shi, Zugui
[4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines
author_sort Zhong, Guofu
title [4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines
title_short [4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines
title_full [4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines
title_fullStr [4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines
title_full_unstemmed [4+2] Annulation of Vinyl Ketones initiated by a Phosphine-Catalyzed Aza-Rauhut-Currier reaction: a practical access to densely functionalized Tetrahydropyridines
title_sort [4+2] annulation of vinyl ketones initiated by a phosphine-catalyzed aza-rauhut-currier reaction: a practical access to densely functionalized tetrahydropyridines
publishDate 2013
url https://hdl.handle.net/10356/99501
http://hdl.handle.net/10220/12915
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