Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines

Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines

Highly enantioselective phase-transfer alkylation of 3-substituted-2-oxindoles with activated bromomethanes is disclosed with a broad substrate scope by using bicyclic guanidinium as a catalyst and a Lewis acid as the co-catalyst. The alkylation adducts are versatile intermediates to accomplish the...

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Main Authors: Jiang, Zhiyong, Chen, Wenchao, Yang, Wenguo, Yan, Lin, Tan, Choon-Hong
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Subjects:
DRNTU::Science::Chemistry
Online Access:https://hdl.handle.net/10356/99510
http://hdl.handle.net/10220/17449
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-995102020-03-07T12:34:46Z Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines Jiang, Zhiyong Chen, Wenchao Yang, Wenguo Yan, Lin Tan, Choon-Hong School of Physical and Mathematical Sciences DRNTU::Science::Chemistry Highly enantioselective phase-transfer alkylation of 3-substituted-2-oxindoles with activated bromomethanes is disclosed with a broad substrate scope by using bicyclic guanidinium as a catalyst and a Lewis acid as the co-catalyst. The alkylation adducts are versatile intermediates to accomplish the syntheses of pyrroloindolines and furoindolines. 2013-11-08T04:48:44Z 2019-12-06T20:08:13Z 2013-11-08T04:48:44Z 2019-12-06T20:08:13Z 2013 2013 Journal Article Chen, W., Yang, W., Yan, L., Tan, C.-H., & Jiang, Z. (2013). Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines. Chemical communications, 49(84), 9854-9856. https://hdl.handle.net/10356/99510 http://hdl.handle.net/10220/17449 10.1039/c3cc46111d en Chemical communications
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Science::Chemistry
spellingShingle DRNTU::Science::Chemistry
Jiang, Zhiyong
Chen, Wenchao
Yang, Wenguo
Yan, Lin
Tan, Choon-Hong
Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines
description Highly enantioselective phase-transfer alkylation of 3-substituted-2-oxindoles with activated bromomethanes is disclosed with a broad substrate scope by using bicyclic guanidinium as a catalyst and a Lewis acid as the co-catalyst. The alkylation adducts are versatile intermediates to accomplish the syntheses of pyrroloindolines and furoindolines.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Jiang, Zhiyong
Chen, Wenchao
Yang, Wenguo
Yan, Lin
Tan, Choon-Hong
format Article
author Jiang, Zhiyong
Chen, Wenchao
Yang, Wenguo
Yan, Lin
Tan, Choon-Hong
author_sort Jiang, Zhiyong
title Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines
title_short Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines
title_full Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines
title_fullStr Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines
title_full_unstemmed Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines
title_sort bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation : direct access to pyrroloindolines and furoindolines
publishDate 2013
url https://hdl.handle.net/10356/99510
http://hdl.handle.net/10220/17449
_version_ 1681034660410294272

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