Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent

Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent

Trypanosoma brucei is a parasite that causes African sleeping sickness in humans and nagana in livestock and is transmitted by the tsetse fly. There is an urgent need for the development of new drugs against African trypanosomiasis due to the lack of vaccines and effective drugs. Orlistat (also call...

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Bibliographic Details
Main Authors: Ngai, Mun Hong, Liu, Kai, Sheriff, Omar, Lear, Martin James, Sze, Siu Kwan, He, Cynthia Y., Yao, Shao Q., Yang, Peng-Yu, Wang, Min
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/99512
http://hdl.handle.net/10220/12894
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/99512
http://hdl.handle.net/10220/12894

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