Morphine and galectin-1 modulate HIV-1 infection of human monocyte-derived macrophages

• Main Authors: Nair, B., Sykes, D. E., Mammen, M. J., Hui, R., Schwartz, Stanley A., Reynolds, Jessica L., Prasad, Paras N., Mahajan, Supriya D., Law, Wing-Cheung, Aalinkeel, Ravikumar, Yong, Ken-Tye
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Electrical and electronic engineering
• Online Access: https://hdl.handle.net/10356/99515; http://hdl.handle.net/10220/13000
• Institution: Nanyang Technological University

Morphine is a widely abused, addictive drug that modulates immune function. Macrophages are a primary reservoir of HIV-1; therefore, they play a role in the development of this disease, as well as impact the overall course of disease progression. Galectin-1 is a member of a family of β-galactoside-b...