Cobalt-catalyzed ortho alkylation of aromatic imines with primary and secondary alkyl halides

• المؤلفون الرئيسيون: Gao, Ke, Yoshikai, Naohiko
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Chemistry::Organic chemistry
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/99605; http://hdl.handle.net/10220/17457
• المؤسسة: Nanyang Technological University

We report here cobalt–N-heterocyclic carbene catalytic systems for the ortho alkylation of aromatic imines with alkyl chlorides and bromides, which allows the introduction of a variety of primary and secondary alkyl groups at room temperature. The stereochemical outcomes of the reaction of secondary...