On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein

10.4161/cc.27273

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Main Authors: ElSawy, K.M., Verma, C.S., Lane, D.P., Caves, L.S.D.
Other Authors: BIOLOGICAL SCIENCES
Format: Article
Published: 2014
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Online Access:http://scholarbank.nus.edu.sg/handle/10635/101301
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spelling sg-nus-scholar.10635-1013012023-10-26T09:22:44Z On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein ElSawy, K.M. Verma, C.S. Lane, D.P. Caves, L.S.D. BIOLOGICAL SCIENCES Brownian dynamics simulation Encounter complex Kinetics-based drug discovery MDM2 protein Nutlin stereoselectivity Residence time Stereoselectivity 10.4161/cc.27273 Cell Cycle 12 24 3727-3735 2014-10-27T08:35:40Z 2014-10-27T08:35:40Z 2013-12-15 Article ElSawy, K.M., Verma, C.S., Lane, D.P., Caves, L.S.D. (2013-12-15). On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein. Cell Cycle 12 (24) : 3727-3735. ScholarBank@NUS Repository. https://doi.org/10.4161/cc.27273 15384101 http://scholarbank.nus.edu.sg/handle/10635/101301 000330524800011 Scopus
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic Brownian dynamics simulation
Encounter complex
Kinetics-based drug discovery
MDM2 protein
Nutlin stereoselectivity
Residence time
Stereoselectivity
spellingShingle Brownian dynamics simulation
Encounter complex
Kinetics-based drug discovery
MDM2 protein
Nutlin stereoselectivity
Residence time
Stereoselectivity
ElSawy, K.M.
Verma, C.S.
Lane, D.P.
Caves, L.S.D.
On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein
description 10.4161/cc.27273
author2 BIOLOGICAL SCIENCES
author_facet BIOLOGICAL SCIENCES
ElSawy, K.M.
Verma, C.S.
Lane, D.P.
Caves, L.S.D.
format Article
author ElSawy, K.M.
Verma, C.S.
Lane, D.P.
Caves, L.S.D.
author_sort ElSawy, K.M.
title On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein
title_short On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein
title_full On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein
title_fullStr On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein
title_full_unstemmed On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein
title_sort on the origin of the stereoselective affinity of nutlin-3 geometrical isomers for the mdm2 protein
publishDate 2014
url http://scholarbank.nus.edu.sg/handle/10635/101301
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