On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein
10.4161/cc.27273
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sg-nus-scholar.10635-1013012023-10-26T09:22:44Z On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein ElSawy, K.M. Verma, C.S. Lane, D.P. Caves, L.S.D. BIOLOGICAL SCIENCES Brownian dynamics simulation Encounter complex Kinetics-based drug discovery MDM2 protein Nutlin stereoselectivity Residence time Stereoselectivity 10.4161/cc.27273 Cell Cycle 12 24 3727-3735 2014-10-27T08:35:40Z 2014-10-27T08:35:40Z 2013-12-15 Article ElSawy, K.M., Verma, C.S., Lane, D.P., Caves, L.S.D. (2013-12-15). On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein. Cell Cycle 12 (24) : 3727-3735. ScholarBank@NUS Repository. https://doi.org/10.4161/cc.27273 15384101 http://scholarbank.nus.edu.sg/handle/10635/101301 000330524800011 Scopus |
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Brownian dynamics simulation Encounter complex Kinetics-based drug discovery MDM2 protein Nutlin stereoselectivity Residence time Stereoselectivity |
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Brownian dynamics simulation Encounter complex Kinetics-based drug discovery MDM2 protein Nutlin stereoselectivity Residence time Stereoselectivity ElSawy, K.M. Verma, C.S. Lane, D.P. Caves, L.S.D. On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein |
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10.4161/cc.27273 |
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BIOLOGICAL SCIENCES |
author_facet |
BIOLOGICAL SCIENCES ElSawy, K.M. Verma, C.S. Lane, D.P. Caves, L.S.D. |
format |
Article |
author |
ElSawy, K.M. Verma, C.S. Lane, D.P. Caves, L.S.D. |
author_sort |
ElSawy, K.M. |
title |
On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein |
title_short |
On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein |
title_full |
On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein |
title_fullStr |
On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein |
title_full_unstemmed |
On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein |
title_sort |
on the origin of the stereoselective affinity of nutlin-3 geometrical isomers for the mdm2 protein |
publishDate |
2014 |
url |
http://scholarbank.nus.edu.sg/handle/10635/101301 |
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1781787358921752576 |