On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein

On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein

10.4161/cc.27273

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Bibliographic Details
Main Authors: ElSawy, K.M., Verma, C.S., Lane, D.P., Caves, L.S.D.
Other Authors: BIOLOGICAL SCIENCES
Format: Article
Published: 2014
Subjects:
Brownian dynamics simulation
Encounter complex
Kinetics-based drug discovery
MDM2 protein
Nutlin stereoselectivity
Residence time
Stereoselectivity
Online Access:http://scholarbank.nus.edu.sg/handle/10635/101301
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Institution: National University of Singapore

Internet

http://scholarbank.nus.edu.sg/handle/10635/101301

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