Determination of the investigational anti-cancer drug 5,6- dimethylxanthenone-4-acetic acid and its acyl glucuronide in Caco-2 monolayers by liquid chromatography with fluorescence detection: Application to transport studies

Determination of the investigational anti-cancer drug 5,6- dimethylxanthenone-4-acetic acid and its acyl glucuronide in Caco-2 monolayers by liquid chromatography with fluorescence detection: Application to transport studies

10.1016/j.jchromb.2004.06.009

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Bibliographic Details
Main Authors: Zhou, S., Feng, X., Kestell, P., Baguley, B.C., Paxton, J.W.
Other Authors: PHARMACY
Format: Article
Published: 2014
Subjects:
5,6-dimethylxanthenone-4-acetic acid
AP
apical
basolateral
BL
CYP
cytochrome P450
dimethyl sulphoxide
DMSO
DMXAA
DMXAA acyl glucuronide
DMXAA-G
Hank's balanced salt solution
HBSS
HEPES
N-[2-hydroxyethyl]piperazine-N′-[4- butanesulfonic acid]
Online Access:http://scholarbank.nus.edu.sg/handle/10635/105808
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Institution: National University of Singapore
Description
Summary:10.1016/j.jchromb.2004.06.009

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